How to detect heparin by handheld Raman spectroscopy?
Good news! Handheld spectrometer, which is poducted by Optosky, successfully detected heparin. On October 29, 2019, Brazil tested the heparin signal using Optosky's portable spectrometer. Prior to this, heparin could not be tested using the Truscan and NanoRam instruments. This is a huge success for Optosky's handheld spectrometer.
Heparin is first named from the liver. It is composed of glucosamine, L-iduronic acid, N-acetylglucosamine and D-glucuronic acid. The average molecular weight is 15KD, which is strongly acidic. It is also found in tissues such as the lungs, blood vessel walls, and intestinal mucosa. It is a natural anticoagulant substance in animals. Naturally found in mast cells, it is now mainly extracted from bovine lung or porcine small intestine mucosa.
As an anticoagulant, heparin is a multimer of two polysaccharides that are alternately linked and has anticoagulant effects in vitro and in vivo. Clinically, it is mainly used for thromboembolic diseases, myocardial infarction, cardiovascular surgery, cardiac catheterization, extracorporeal circulation, hemodialysis, and the like. With the advancement of pharmacology and clinical medicine, the application of heparin has been expanding.
ATR6500 of Optosky is the 4th generation handheld Raman analyzer, with compact size, lightweight (450g), and easy-to-held, it can be widely applied to industries of customs. Excellent spectral identification algorithm are embedded in Handheld Raman spectrometers to easily identify substance, and enable users to add their own spectral data. It employs Android system,simple interface,5.5" high definition screen, double cameras of 13-mega plus 8-mega taking evidence pictures in the field, multiple modes of inbuilt WIFI, Bluetooth, GPS etc.
Optosky provides full technical support and services, including spectral library building, method & verification, IQ/OQ/PQ validation etc.
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