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Drug companies optimize their production operations across the world to stay competitive in the pharmaceutical industry. However, production delocalization forces them to thoroughly analyze the incoming raw materials for quality control, product safety and regulatory purposes, which can eventually increase the cost. Additionally, the industry is shifting from a representative sampling method towards a total traceability of the incoming materials, thus affecting factory efficiency and operational costs. Hence, stringent control over the quality and safety of all materials which used in the production of a pharmaceuticals is essential.

This article covers the affordability and advantages of using handheld Raman spectrometer for this purpose.

Optosky Photonic Inc., the applied spectral knowledge company, has introduced ATR3200 dual-band Raman spectrometer integrate two wavelengths laser sources to detect small sample in many cases in lab is uncertain of wavelengths better for their application. It requires no contact, no treatment to make an undestructive detect. This instrument has advantages of high performance-to-ratio, smart size can detect liquids, including fabrics, biology, alcoholics, crystals etc.

Carbon is the most abundant element in the nature. It has low cost, long life, high temperature resistance, diverse stuctures, and high specific capacitance of carbon materials. It is currently the most active research direction in the field of electrochemistry. It is also the one of the inportant topics in the development of clean & renewable energy, and play a vital role in electeic cars, mobile communications, solar and wind power, aerospace and defense technology, etc.

The research of carbon nanotechnology is quite active in recent years. Common carbon materials is graphene, graphite, carbon nanotubes and carbon black, etc. They all show the unique electrical conductivity, thermal conductivity and mechanical strength. It's all due to the unique structure of each allogtaft. However, how to describe the types and quality of different carbon nanomaterials in a simple quite way to effectively monitor, control production and later application is an inportant issue. Because of the molecular vibration characteristics of nanomaterials, Raman spectroscopy has been widely used in the research field of carbon nanomatericals. It is a fast, simple, and ideal analysis tool for characterizing carbon materials.

The drug safety affects people's quality of life, physical health and even risks their lives. It also concerns the economic development, social stability, and it even related to proliferation of ethnic．During the past decades, there has been big increase in the number of reported case of drug safety. Counterfeit pharmaceutical products have become a serious worldwide problem，especially in the developing countries. Many methods have been developed to identify the counterfeit(s) and adulterant(s), including chemistry,  spectroscopy, and chromatographic separation-based methods．Some chromatography methods which have served as the resort along this track of analytical strategy,such as high performance liquid chromatography coupled with mass spectrometry(HPLC_MS).