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Nov 21
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How to identify pharmaceutical raw materials and excipients by Raman instrument?

Starch is a complex polymer. It consists of glycoside bonds connecting glucose units. And because of its multifunctionality, it is used by important medicinal accessories. Solid starch has the motion of granular. The varieties and growing environment of starch influence its size and it is divided into straight chain and branched chain. The starch of staight chain has 50 to 6000 glucosamine residues for aggregation. The branched chain starch has, A , B & C, three kinds of chain. C chain is backbone with more than 60 glucosamine residues and a terminal saccharide residues. B chain is the branched chain of C, its aggregation has 45 to 55 glucosamine residues. A is the branched chain of B with 14 to 18 glucosamine residues. Different chain has different nature and its own effect by ingredients.

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Nov 20
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Do you know the all-automatic & high throughput portable Raman analyzer?

As we all know, Raman testing for one sample usually costs 10s or more time. Some experiments perform multiple experiments in order to obtain a higher signal-to-noise ratio, and the experiment time is longer. It takes longer time for the 1064nm Raman spectrometer to scan samples, because of weak excitation efficiency, and low response rate of infrared sensors etc. In this way, researchers consume a lot of time and effort to repeat test labors if they want to measure 100 samples, it may be take hours or even a whole day.

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Nov 19
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Good News: ATR8000 Protable Raman Analyzer First appeard

ATR8000 full-auto & high throughput Portable Raman Analyzer is a all-auto detection instrument for improving detection throughput, reducing workload & protecting the health of testing personnel.

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Nov 11
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How to Controll Drugs and Narcotics by Safity, Non-destructive Identification?

It is a non-contact and non-destructive and does not require any sample preparation for raman spectrometer. However, further investigations of the same specimen to confirm results can preserve small traces of evidence.Additionally, the the high spatial tesolution of confocal system enables performing a complete analusis withe small sample volume.In the field of Forensic Science, they make the technique as an efficient and robust analytical method.

The analyst often needs to analyze mixtures of drug particles and cutting agents. Manitol, myoinositol and sorbitol have been analyzed as possible cutting agents and their Raman spectrometer are depicted in Figure 3. The results clearly show that the spectra of cutting agents differ from each other as well as from the reported spectra of drugs.

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Nov 11
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How to fast identify liquid reagent on quanitification method?

According to the traditional method, Raman spectroscopy is considered to be unsuitable for quantitative applications due to poor signal strength stability, strong background signals such as fluorescence, and the like, even in many textbooks. But in fact, material information contained in Raman spectroscopy Not only the nature of the material, but also the information about the quality of the material. In principle, as long as the current difficult problem is solved in the method, Raman spectroscopy is a simple, fast and non-destructive testing method, not only a powerful tool on qualification, but also on quantification.

In order to solve this problem, Sipatt proposed a multi-technology centered on "high-order derivatives to ensure data selectivity" and successfully applied to Raman spectrometers. In this paper, we will introduce a salicylic acid saponin as an example to introduce a method for the detection of salicylic acid and benzoic acid in salicylic acid bismuth, and the accuracy is expressed as 3% within the relative error. Optosky Raman spectrometers make a fast, viable, no-module method for quantitative analysis of liquid formulations.

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